Antibody response to anti-A/New Jersey/76 vaccines.
Identifieur interne : 000761 ( Main/Exploration ); précédent : 000760; suivant : 000762Antibody response to anti-A/New Jersey/76 vaccines.
Auteurs : C. Hannoun ; M. Barme ; C. Sérié ; H. Beck ; J. Aquino ; M. ThibonSource :
- Developments in biological standardization [ 0301-5149 ]
Descripteurs français
- KwdFr :
- MESH :
- Wicri :
- geographic : France.
English descriptors
- KwdEn :
- MESH :
- chemical : Antibodies, Viral, Hemagglutinins, Viral, Influenza Vaccines.
- geographic : France.
- immunology : Influenza A virus.
- Adult, Age Factors, Aged, Antibody Formation, Humans, Immunization, Secondary, Middle Aged.
Abstract
Experimental inactivated influenza vaccines prepared with strain X 53, derived from A/New Jersey/76 virus were injected to several groups of subjects. Different compositions of vaccine were used and the subjects were selected from different age groups. Antibody responses were measured 15 days after vaccination; it was then possible to evaluate the conversion rates, the percentages of subjects showing a protective level of antibodies and the average level of antibodies. The results show that a very small dose of antigen, probably acting as a booster, gives very good results in the older age group. On the other hand, young adults (below 23) react to a much lower degree to the vaccine. The results are discussed in relation to the age distribution of preexisting antibodies in the experimental groups and in the general population in France.
PubMed: 604105
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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<author><name sortKey="Hannoun, C" sort="Hannoun, C" uniqKey="Hannoun C" first="C" last="Hannoun">C. Hannoun</name>
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<author><name sortKey="Barme, M" sort="Barme, M" uniqKey="Barme M" first="M" last="Barme">M. Barme</name>
</author>
<author><name sortKey="Serie, C" sort="Serie, C" uniqKey="Serie C" first="C" last="Sérié">C. Sérié</name>
</author>
<author><name sortKey="Beck, H" sort="Beck, H" uniqKey="Beck H" first="H" last="Beck">H. Beck</name>
</author>
<author><name sortKey="Aquino, J" sort="Aquino, J" uniqKey="Aquino J" first="J" last="Aquino">J. Aquino</name>
</author>
<author><name sortKey="Thibon, M" sort="Thibon, M" uniqKey="Thibon M" first="M" last="Thibon">M. Thibon</name>
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<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="1977">1977 Jun 1-3</date>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Antibody response to anti-A/New Jersey/76 vaccines.</title>
<author><name sortKey="Hannoun, C" sort="Hannoun, C" uniqKey="Hannoun C" first="C" last="Hannoun">C. Hannoun</name>
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<author><name sortKey="Barme, M" sort="Barme, M" uniqKey="Barme M" first="M" last="Barme">M. Barme</name>
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<author><name sortKey="Serie, C" sort="Serie, C" uniqKey="Serie C" first="C" last="Sérié">C. Sérié</name>
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<author><name sortKey="Beck, H" sort="Beck, H" uniqKey="Beck H" first="H" last="Beck">H. Beck</name>
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<author><name sortKey="Aquino, J" sort="Aquino, J" uniqKey="Aquino J" first="J" last="Aquino">J. Aquino</name>
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<author><name sortKey="Thibon, M" sort="Thibon, M" uniqKey="Thibon M" first="M" last="Thibon">M. Thibon</name>
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<series><title level="j">Developments in biological standardization</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult (MeSH)</term>
<term>Age Factors (MeSH)</term>
<term>Aged (MeSH)</term>
<term>Antibodies, Viral (MeSH)</term>
<term>Antibody Formation (MeSH)</term>
<term>France (MeSH)</term>
<term>Hemagglutinins, Viral (MeSH)</term>
<term>Humans (MeSH)</term>
<term>Immunization, Secondary (MeSH)</term>
<term>Influenza A virus (immunology)</term>
<term>Influenza Vaccines (MeSH)</term>
<term>Middle Aged (MeSH)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte (MeSH)</term>
<term>Adulte d'âge moyen (MeSH)</term>
<term>Anticorps antiviraux (MeSH)</term>
<term>Facteurs âges (MeSH)</term>
<term>France (MeSH)</term>
<term>Humains (MeSH)</term>
<term>Hémagglutinines virales (MeSH)</term>
<term>Production d'anticorps (MeSH)</term>
<term>Rappel de vaccin (MeSH)</term>
<term>Sujet âgé (MeSH)</term>
<term>Vaccins antigrippaux (MeSH)</term>
<term>Virus de la grippe A (immunologie)</term>
</keywords>
<keywords scheme="MESH" type="chemical" xml:lang="en"><term>Antibodies, Viral</term>
<term>Hemagglutinins, Viral</term>
<term>Influenza Vaccines</term>
</keywords>
<keywords scheme="MESH" type="geographic" xml:lang="en"><term>France</term>
</keywords>
<keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Virus de la grippe A</term>
</keywords>
<keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Influenza A virus</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Age Factors</term>
<term>Aged</term>
<term>Antibody Formation</term>
<term>Humans</term>
<term>Immunization, Secondary</term>
<term>Middle Aged</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Anticorps antiviraux</term>
<term>Facteurs âges</term>
<term>France</term>
<term>Humains</term>
<term>Hémagglutinines virales</term>
<term>Production d'anticorps</term>
<term>Rappel de vaccin</term>
<term>Sujet âgé</term>
<term>Vaccins antigrippaux</term>
</keywords>
<keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>France</term>
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<front><div type="abstract" xml:lang="en">Experimental inactivated influenza vaccines prepared with strain X 53, derived from A/New Jersey/76 virus were injected to several groups of subjects. Different compositions of vaccine were used and the subjects were selected from different age groups. Antibody responses were measured 15 days after vaccination; it was then possible to evaluate the conversion rates, the percentages of subjects showing a protective level of antibodies and the average level of antibodies. The results show that a very small dose of antigen, probably acting as a booster, gives very good results in the older age group. On the other hand, young adults (below 23) react to a much lower degree to the vaccine. The results are discussed in relation to the age distribution of preexisting antibodies in the experimental groups and in the general population in France.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">604105</PMID>
<DateCompleted><Year>1978</Year>
<Month>04</Month>
<Day>17</Day>
</DateCompleted>
<DateRevised><Year>2005</Year>
<Month>11</Month>
<Day>22</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Print">0301-5149</ISSN>
<JournalIssue CitedMedium="Print"><Volume>39</Volume>
<PubDate><MedlineDate>1977 Jun 1-3</MedlineDate>
</PubDate>
</JournalIssue>
<Title>Developments in biological standardization</Title>
<ISOAbbreviation>Dev. Biol. Stand.</ISOAbbreviation>
</Journal>
<ArticleTitle>Antibody response to anti-A/New Jersey/76 vaccines.</ArticleTitle>
<Pagination><MedlinePgn>249-52</MedlinePgn>
</Pagination>
<Abstract><AbstractText>Experimental inactivated influenza vaccines prepared with strain X 53, derived from A/New Jersey/76 virus were injected to several groups of subjects. Different compositions of vaccine were used and the subjects were selected from different age groups. Antibody responses were measured 15 days after vaccination; it was then possible to evaluate the conversion rates, the percentages of subjects showing a protective level of antibodies and the average level of antibodies. The results show that a very small dose of antigen, probably acting as a booster, gives very good results in the older age group. On the other hand, young adults (below 23) react to a much lower degree to the vaccine. The results are discussed in relation to the age distribution of preexisting antibodies in the experimental groups and in the general population in France.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Hannoun</LastName>
<ForeName>C</ForeName>
<Initials>C</Initials>
</Author>
<Author ValidYN="Y"><LastName>Barme</LastName>
<ForeName>M</ForeName>
<Initials>M</Initials>
</Author>
<Author ValidYN="Y"><LastName>Sérié</LastName>
<ForeName>C</ForeName>
<Initials>C</Initials>
</Author>
<Author ValidYN="Y"><LastName>Beck</LastName>
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<Author ValidYN="Y"><LastName>Aquino</LastName>
<ForeName>J</ForeName>
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<Author ValidYN="Y"><LastName>Thibon</LastName>
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<Initials>M</Initials>
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<Language>eng</Language>
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<MedlineJournalInfo><Country>Switzerland</Country>
<MedlineTA>Dev Biol Stand</MedlineTA>
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<MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
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<MeshHeading><DescriptorName UI="D000367" MajorTopicYN="N">Age Factors</DescriptorName>
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<MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
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<MeshHeading><DescriptorName UI="D000914" MajorTopicYN="N">Antibodies, Viral</DescriptorName>
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<MeshHeading><DescriptorName UI="D000917" MajorTopicYN="N">Antibody Formation</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005602" MajorTopicYN="N" Type="Geographic">France</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006389" MajorTopicYN="N">Hemagglutinins, Viral</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007117" MajorTopicYN="N">Immunization, Secondary</DescriptorName>
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<MeshHeading><DescriptorName UI="D009980" MajorTopicYN="N">Influenza A virus</DescriptorName>
<QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName>
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<MeshHeading><DescriptorName UI="D007252" MajorTopicYN="Y">Influenza Vaccines</DescriptorName>
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<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
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<PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1977</Year>
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<affiliations><list></list>
<tree><noCountry><name sortKey="Aquino, J" sort="Aquino, J" uniqKey="Aquino J" first="J" last="Aquino">J. Aquino</name>
<name sortKey="Barme, M" sort="Barme, M" uniqKey="Barme M" first="M" last="Barme">M. Barme</name>
<name sortKey="Beck, H" sort="Beck, H" uniqKey="Beck H" first="H" last="Beck">H. Beck</name>
<name sortKey="Hannoun, C" sort="Hannoun, C" uniqKey="Hannoun C" first="C" last="Hannoun">C. Hannoun</name>
<name sortKey="Serie, C" sort="Serie, C" uniqKey="Serie C" first="C" last="Sérié">C. Sérié</name>
<name sortKey="Thibon, M" sort="Thibon, M" uniqKey="Thibon M" first="M" last="Thibon">M. Thibon</name>
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